Anti-STK24 Polyclonal Antibody,BR

英文名称： Anti-STK24 Polyclonal Antibody
中文名称： 丝氨酸/苏氨酸激酶24抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

靶标： STK24
别名： HEL-S-95, Mammalian STE20 like protein kinase 3, Mammalian STE20-like protein kinase 3, Mammalian STE20-like protein kinase 3 C-terminal, Mammalian STE20-like protein kinase 3 N-terminal, Mammalian sterile 20-like 3, MST-3, MST3/C, MST3/N, MST3B, serine threonine kinase 24, Serine/threonine kinase 24 (Ste20, yeast homolog), Serine/threonine-protein kinase 24 12 kDa subunit, Serine/threonine-protein kinase 24, STE20 homolog yeast, STE20 like kinase MST3, STE20-like kinase MST3, Stk24, STK24_HUMAN, STK3
背景说明： Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
Swiss Prot： Q9Y6E0
Gene ID： 8428
亚细胞定位： Cytoplasm Cell membrane Nucleus
免疫原： Recombinant protein of human STK24
Public Immunogen Range： 81-432aa
理论分子量： 48/49kDa

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

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