1-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-4-硫代-3,4-二氢嘧啶-2(1H)-酮,≥98%

4-Thiouridine

(订货以英文名为准)

产品编号：T91790 CAS：13957-31-8 分子式：C₉H₁₂N₂O₅S MDL：MFCD00006538 品牌：Acmec

1-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-4-硫代-3,4-二氢嘧啶-2(1H)-酮

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中文名称：

4-巯基尿苷

英文名称：

4-Thiouridine

CAS No.：

13957-31-8

分子式：

C₉H₁₂N₂O₅S

分子量：

260.27

性状：

淡黄色粉末

密度：

1.72±0.1 g/cm3(Predicted)

熔点：

139-140°C (ethanol )

保存条件：

-20°C

InChIKey：

ZLOIGESWDJYCTF-XVFCMESISA-N

InChI：

InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1

Pubchem ID：

3032615

危化品级别：

关于的化合物详细属性等信息，点击“13957-31-8”

4-巯基尿苷用途是什么？

提问时间：2021/6/30 13:00:18

4-巯基尿苷是做什么用的?哪里可以用到4-巯基尿苷?

回复内容：

admin2021-08-30 09:42:27

4-巯基尿苷4-硫代尿苷用途4-Thiouridine, also known as 4-SU, is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.