Recombinant Human IL-5,BR

别名： Interleukin-5;IL-5;B-cell differentiation factor I;Eosinophil differentiation factor;T-cell replacing factor;TRF;IL5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： IL-5 is expressed in eosinophils，NK cells，TC2 CD8+ T cells，mast cells，CD45+ CD4+ T cells，gamma delta T cells and IL-1 beta activated endothelial cells.IL-5 acts as a growth and differentiation factor for both B cells and eosinophils.Relative to B cells，IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells.In addition，it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils.These include the down modulation of Mac-1，the upregulation of receptors for IgA and IgG，the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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