Anti-BCL2L11 Polyclonal Antibody,BR

英文名称:Anti-BCL2L11 Polyclonal Antibody
宿主:Rabbit
别名:BAM;BIM;BOD
交叉反应:Human Mouse Rat
应用:WB IF
稀释比例:WB 1:500-1:2000. IF 1:100-1:200.
蛋白分子量:22/13/19/9/4kDa
Gene ID:10018
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human BCL2L11
亚细胞定位:Endomembrane system Mitochondrion Peripheral membrane protein
Swiss Prot:O43521
背景资料:The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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