Anti-E2F1 Monoclonal Antibody,BR

英文名称： Anti-E2F1 Monoclonal Antibody
中文名称： E2F1单克隆抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG2b
克隆号： 4G8-2C2-C12
交叉反应： Rat ; Mouse ; Human
应用： IP ; IF/ICC ; WB
稀释比例： WB 1:500-1000. IF/ICC 1:50-200. IP 1:20.

靶标： E2F1
别名： E2F-1;RBAP1;RBBP3;RBP3
背景说明： The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Swiss Prot： Q01094
Gene ID： 1869
亚细胞定位： Nucleus
研究领域： 细胞生物学 ; 神经学 ; 表观遗传
免疫原： Recombinant protein of human E2F1
理论分子量： 47kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.
运输条件： 冷冻运输

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。