Recombinant Human Leptin,BR

别名： Leptin;Obese Protein;Obesity Factor;LEP;OB;OBS
英文名称： Recombinant Human Leptin
中文名称： 重组人Leptin
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance.Leptin functions via signaling pathways involving OB-R in hypothalamus.Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level.When mutations are introduced in obese gene，mice with impaired function of leptin are massively obese and in high risk of diabetes.Leptin deficiency reduces metablic rate.Leptin deficient mice are less active and with lower body temperature than normal animals.Human Leptin shares approximately 84% sequence identity with the mouse protein.Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.
来源： E.coli

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

Recombinant Human Leptin is produced by our E.coli expression system and the target gene encoding Val22-Cys167 is expressed.

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