别名：盐酸拓扑替康;盐酸拓扑替康;C23H24ClN3O5
CAS：119413-54-6 分子式：C₂₃H₂₄ClN₃O₅ 分子量：457.91 MDL：MFCD00866235

T64221	CAS:119413-54-6	盐酸拓扑替康, 98%, Acmec	价格库存收藏产品

T64220	CAS:119413-54-6	盐酸拓扑替康, 分析对照品,HPLC≥98%, Acmec	价格库存收藏产品

TCI-T2795	CAS:119413-54-6	盐酸拓扑替康, >95.0%(LC&T), TCI	价格库存收藏产品

化合物信息
安全信息

中文名称：

盐酸拓扑替康

英文名称：

Topotecan hydrochloride

CAS No.：

119413-54-6

分子式：

C₂₃H₂₄ClN₃O₅

分子量：

457.91

InChIKey：

DGHHQBMTXTWTJV-BQAIUKQQSA-N

InChI：

InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1

Pubchem ID：

60699

危险品标志：

海关编码：

2942000000

信号词：

Warning

危害声明：

H302-H315-H319-H332-H335

警示性声明：

P280-P305+P351+P338-P310

危险类别码：

R25

安全说明：

S26; S36/37/39; S45

技术问答

游客JZ2106307930 2021-06-30 12:59

问盐酸拓扑替康用途是什么？

描述：盐酸拓扑替康是做什么用的?哪里可以用到盐酸拓扑替康?

答盐酸拓扑替康用作抗肿瘤药;一种拓扑异构酶I抑制剂。Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.;一种具有抗癌活性的拓扑异构酶I抑制剂。

admin 2021-08-30 09:42

盐酸拓扑替康用作抗肿瘤药;一种拓扑异构酶I抑制剂。Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.;一种具有抗癌活性的拓扑异构酶I抑制剂。

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技术问答

问 盐酸拓扑替康用途是什么？

问盐酸拓扑替康用途是什么？