Recombinant human CYFIP1 protein,BR

基因名： CYFIP1
别名： CY;CYFIP 1;CYFIP1;CYFP1_HUMAN;Cytoplasmic FMR1 interacting protein 1;Cytoplasmic FMR1-interacting protein 1;FLJ45151;KIAA0068;p140sra 1;p140sra-1;P140SRA1;Selective hybridizing clone;SHYC;Specifically Rac1 associated protein 1;Specifically Rac1-associated protein 1;SRA 1;Sra-1;SRA1;
全名： cytoplasmic FMR1 interacting protein 1
英文名称： Recombinant Human CYFIP1 Protein
中文名称： 细胞质FMR1相互作用蛋白1
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q7L576
Gene ID： 23191
交叉反应： Human Mouse (Bovine ZebraFish)
分子量： 41kDa
区间范围： 1-350aa
背景说明： Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.
研究领域： 癌症研究与治疗
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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