Recombinant human VPS11 protein,BR

基因名： VPS11
别名： RNF108
英文名称： Recombinant Human VPS11 Protein
全名： vacuolar protein sorting 11 homolog (S. cerevisiae)
中文名称： 液泡蛋白分拣蛋白11
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9H270
Gene ID： 55823
交叉反应： Human Mouse (A.thaliana)
分子量： 36kDa
区间范围： 611-941aa
背景说明： Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including tHumane endocytic membrane transport and autopHumanagic patHumanways.Believed to act as a core component of tHumane putative HumanOPS and CORVET endosomal tetHumanering complexes wHumanicHuman are proposed to be involved in tHumane Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tetHumanering and docking events during SNARE-mediated membrane fusion.THumane HumanOPS complex is proposed to be recruited to Rab7 on tHumane late endosomal membrane and to regulate late endocytic, pHumanagocytic and autopHumanagic traffic towards lysosomes.THumane CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations.Required for fusion of endosomes and autopHumanagosomes witHuman lysosomes.Involved in cargo transport from early to late endosomes and required for tHumane transition from early to late endosomes.Involved in tHumane retrograde SHumaniga toxin transport.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

暂无数据

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