Recombinant human HERPUD1 protein,BR

基因名： HERPUD1
别名： HERPUD1;HERP;Mif1;SUP
全名： homocysteine-inducible，endoplasmic reticulum stress-inducible，ubiquitin-like domain member 1
英文名称： Recombinant Human HERPUD1 Protein
中文名称： 同型半胱氨酸敏感内质网泛素样结构域蛋白成员1
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 2-7 days, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q15011
Gene ID： 9709
交叉反应： Human Mouse (Gorilla)
分子量： 26kDa
区间范围： 1-232aa
背景说明： The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response.This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system.This gene may play a role in both UPR and ERAD.Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system.This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression.Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.The full-length nature of all transcript variants has not been determined.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： No activity experimental data, to be verified.
标签信息： With a 6×His tag at the N/C-terminus.

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