Recombinant human PPM1A protein,BR

基因名： PPM1A
别名： PP2C-alpha
英文名称： Recombinant Human PPM1A Protein
全名： protein phosphatase 1A (formerly 2C)，magnesium-dependent，alpha isoform
中文名称： 镁依赖型蛋白磷酸酶1Aα亚型
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： P35813
Gene ID： 5494
交叉反应： Human Mouse Rat (Bovine Rabbit)
分子量： 42kDa
区间范围： 1-382aa
背景说明： Enzyme with a broad specificity.Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.Dephosphorylates PRKAA1 and PRKAA2.Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
研究领域： 炎症与自身免疫疾病
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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