Recombinant human NMNAT2 protein,BR

基因名： NMNAT2
别名： C1orf15；KIAA0479
英文名称： Recombinant Human NMNAT2 Protein
全名： nicotinamide nucleotide adenylyltransferase 2
中文名称： 烟酰胺单核苷酸腺苷转移酶2
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9BZQ4
Gene ID： 23057
交叉反应： Human Mouse Rat (Gorilla Bovine)
分子量： 33kDa
区间范围： 1-303aa
背景说明： Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity).Catalyzes the formation of NAD+from nicotinamide mononucleotide (NMN) and ATP.Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency.Cannot use triazofurin monophosphate (TrMP) as substrate.Also catalyzes the reverse reaction, i.e.the pyrophosphorolytic cleavage of NAD+.For the pyrophosphorolytic activity prefers NAD+, NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively.Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NaADP+.Axon survival factor required for the maintenance of healthy axons: acts by delaying Wallerian axon degeneration, an evolutionarily conserved process that drives the loss of damaged axons (By similarity).
研究领域： 癌症研究与治疗
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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