Recombinant human RNF185 protein,BR

基因名： RNF185
别名： BSK65-MONO1;BSK65-MONO2;BSK65-PANC1;BSK65-PANC2;BSK65-TEST1;BSK65-TEST2;BSK65-TEST3;FLJ38628;ring finger protein 185
英文名称： Recombinant Human RNF185 Protein
全名： ring finger protein 185
中文名称： 锌指蛋白185
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q96GF1
Gene ID： 91445
交叉反应： Human Mouse Rat (Gorilla Chicken)
分子量： 21kDa
区间范围： 1-192aa
背景说明： E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693).Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation (PubMed:27485036).Protects cells from ER stress-induced apoptosis (PubMed:27485036).Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway (PubMed:24019521).Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (PubMed:24019521).
研究领域： 炎症与自身免疫疾病
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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