Recombinant human ALKBH4 protein,BR

基因名： ALKBH4
别名： 2010004B12Rik;ABH4;Abj4;AlkB，alkylation repair homolog 4 (E. coli);Alkylated DNA repair protein alkB homolog 4;FLJ20013;Probable alpha-ketoglutarate dependent dioxygenase ABH4;RGD1308608;
英文名称： Recombinant Human ALKBH4 Protein
全名： alkB，alkylation repair homolog 4 (E. coli)
中文名称： ALKB 烷基化修复同系物4
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9NXW9
Gene ID： 54784
交叉反应： Human Mouse
分子量： 33kDa
区间范围： 1-302aa
背景说明： Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes (PubMed:23673617).Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration (PubMed:23673617).In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N6-methyladenosine) DNA, thereby regulating Polycomb silencing (By similarity).
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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