Recombinant human SPIN1 protein,BR

基因名： SPIN1
别名： SPIN;TDRD24;spindlin-1
英文名称： Recombinant Human SPIN1 Protein
全名： spindlin 1
中文名称： 纺锤体蛋白1
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9Y657
Gene ID： 10927
交叉反应： Human Mouse Rat (Gorilla)
分子量： 30kDa
区间范围： 1-262aa
背景说明： Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2.In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551).Overexpression induces metaphase arrest and chromosomal instability.Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006).May play a role in cell-cycle regulation during the transition from gamete to embryo.Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
研究领域： 癌症研究与治疗
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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