Recombinant human NARF protein,BR

基因名： NARF
别名： DKFZp434G0420;FLJ10067;IOP2
英文名称： Recombinant Human NARF Protein
全名： nuclear prelamin A recognition factor
中文名称： 核前层蛋白A识别因子
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9UHQ1
Gene ID： 26502
交叉反应： Human Mouse Rat (Zebrafish)
分子量： 45kDa
区间范围： 1-408aa
背景说明： Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends.Prenylation was initially believed to be important only for membrane attachment.However, another role for prenylation appears to be its importance in protein-protein interactions.The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins.Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif.This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A.The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain.It may be a component of a prelamin A endoprotease complex.The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina.It shares limited sequence similarity with iron-only bacterial hydrogenases.Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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