Recombinant human CHMP4B protein,BR

基因名： CHMP4B
别名： CHMP4B;C20orf178;CHMP4A;CTPP3;CTRCT31;SNF7;SNF7-2;Shax1;VPS32B;Vps32-2;dJ553F4.4
全名： chromatin modifying protein 4B
英文名称： Recombinant Human CHMP4B Protein
中文名称： 染色质修饰蛋白4B
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q9H444
Gene ID： 128866
交叉反应： Human Mouse (Chicken Zebrafish)
分子量： 25kDa
区间范围： 1-224aa
背景说明： This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family.The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes.The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1.The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway.The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding.These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.Mutations in this gene result in autosomal dominant posterior polar cataracts.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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