Recombinant human OPTN protein,BR

基因名： OPTN
别名： OPTN;ALS12;FIP2;GLC1E;HIP7;HYPL;NRP;TFIIIA-INTP;optineurin
全名： optineurin
英文名称： Recombinant Human OPTN Protein
中文名称： 视神经蛋白
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： Q96CV9
Gene ID： 10133
交叉反应： Human Mouse Rat (Zebrafish Chicken Pig Gorilla)
分子量： 38kDa
区间范围： 1-350aa
背景说明： This gene encodes the coiled-coil containing protein optineurin.Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma.Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction.Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.Alternative splicing results in multiple transcript variants encoding the same protein.
研究领域： 炎症与自身免疫疾病
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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