Recombinant human PLOD2 protein,BR

基因名： PLOD2
别名： LH2，Lysyl hydroxylase 2，PLOD2，TLH
英文名称： Recombinant Human PLOD2 Protein
全名： procollagen-lysine，2-oxoglutarate 5-dioxygenase 2
中文名称： 前胶原赖氨酸，2-氧戊二酸5-双加氧酶2
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

Swiss Prot： O00469
Gene ID： 5352
交叉反应： Human Mouse Rat
分子量： 40kDa
区间范围： 1-350aa
背景说明： The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum.The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides.The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks.Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.Mutations in the coding region of this gene are associated with Bruck syndrome.Alternative splicing results in multiple transcript variants encoding different isoforms.
应用： Immunology research
来源： E.coli

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

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