Recombinant Human HSPB11/PP25,BR

别名： Heat Shock Protein Beta-11;Hspb11;Placental Protein 25;PP25;HSPB11;C1orf41
英文名称： Recombinant Human HSPB11/PP25
中文名称： 重组人HSPB11/PP25
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 2mM DTT, 10% Glycerol, pH 8.0.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： 干冰运输

背景说明： Heat Shock Protein β-11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses.HSPB11 is composed of an IFT complex B composed of IFT88，IFT57，TRAF3IP1，IFT52，IFT27，HSPB11 and IFT20 and is detected in placenta.HSPB11 has beeb shown to form oligomeric complexes and prevent the aggregation of in vitro denaturated aldolase and glyceraldehyde-3-phosphate dehydrogenase in accordance with the chaperone model of HSPB1 and HSPB5.HSPB11 overexpression protected against etoposide-induced cell death that correlated with a decreased release of mitochondrial Cytochrome C into the cytosol.Inhibition of HSP90 function completely abrogated the protective effect of HSPB11.This data suggests that at least in the case of HSPB11，interaction with other chaperone machines besides HSPA1A may contribute to functional specificity and cellular functioning.
来源： E.coli

内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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