Recombinant Human CA125/MUC16,BR

别名： CA125 ovarian cancer antigen;CA125;CA-125;CA125MUC-16;FLJ14303;MUC16;mucin 16,cell surface associated;mucin-16
英文名称： Recombinant Human CA125/MUC16
中文名称： 重组人CA125/MUC16
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： MUC16，also known as the CA125 antigen，is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.MUC16 is over-expressed by tumor cells including ovarian and mesothelial cancers.The transmembrane form can adhere to mesothelin in the peritoneum，facilitating metastasis of ovarian cancer to the peritoneal cavity.MUC16 also binds galectin-1 on immune cells and enhances its expression on tumor cells.MUC16-expressing tumors adhere to NK cells，down-regulate CD16 and suppress NK response，which may promote immune evasion.MUC16 is also cyclically expressed in the endometrium and may contribute to immune privilege during pregnancy.In the eye，MUC16 and other mucins protect the cornea and keep it hydrated.It is altered on the conjunctival epithelium of patients with non-Sjogren dry eye syndrome.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

暂无数据

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。