Recombinant Human HMGB1/High mobility group protein B1/HMG-1,BR

别名： High Mobility Group Protein B1;High Mobility Group Protein 1;HMG-1;HMGB1;HMG1
英文名称： Recombinant Human HMGB1/High mobility group protein B1/HMG-1
中文名称： 重组人HMGB1/High mobility group蛋白 B1/HMG-1
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM HEPES-Na,p H 7.9，500mM NaCl，0.6mM DTT.
纯度： ≥90% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： High mobility group protein B1 is a member of the HMGB family consisting of three members，HMGB1，HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus.As a nuclear protein，HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival.Meanwhile，it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte，T cell，dendritic cell activities in inflammatory responses.
来源： E.coli

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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