Recombinant Mouse Ectodysplasin Receptor/EDAR,BR

别名： Tumor necrosis factor receptor superfamily member EDAR;Anhidrotic ectodysplasin receptor 1;Downless;Ectodermal dysplasia receptor;Ectodysplasin-A receptor
英文名称： Recombinant Mouse Ectodysplasin Receptor/EDAR
中文名称： 重组小鼠Ectodysplasin Receptor/EDAR
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Ectodysplasin A receptor (EDAR) is a type I transmembrane protein of the TNF-α receptor superfamily which plays a key role in ectodermal differentiation.EDAR was encoded by the mouse downless gene and defective in human dominant and recessive forms of autosomal hypohidrotic ectodermal dysplasia (EDA) syndrome.The extracellular domain of EDAR contains 14 cysteine residues，six of which approximate the TNFRSF cysteine-rich region，the cytoplasmic domain contains a region with homology to the death domains found in other TNFRSF members.EDAR has been suggested to be an early and important promoter of placode development in all ectodermal organs，such as uch as hair follicles，teeth and sweat glands.EDA-A1，the A1 isoform of EDA，is the EDAR ligand.EDA and EDA are implicated in appendage development by the cloning of a gene underlying hypohidrotic ectodermal dysplasia (HED) in mouse and human.HED is characterized by agenesis or malformation of ectoderm-derived appendages，such as teeth，sweat glands and hair follicles，while the skin itself develops normally.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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