Recombinant Human Glypican 3/GPC3/OCI5,BR

别名： Glypican-3;GTR2-2;Intestinal protein OCI-5;MXR7;GPC3;OCI5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Glypican-3/GPC3 is a member of the glypican family.It belongs to the glypican family and is highly expressed in lung，liver，and kidney.It is a heparan sulfate proteoglycan，which is overexpressed in various neoplasms such as hepatocellular carcinoma，malignant melanoma，and testicular yolk sac tumor，and plays an important role in cell growth and differentiation.GPC3 function is tissue dependent.In some tissues，GPC3 acts as a tumor suppressor gene，whereas in others，it acts as an oncofetal protein.GPC3 is a reliable marker for hepatocellular carcinoma.The sensitivity and specificity exceeds both alpha-fetoprotein and hepatocyte-paraffin1.GPC3 immunohistochemistry can aid in the differentiation of testicular germ cell tumors，being expressed in all yolk sac tumors but not in seminomas.GPC3 expression has also been identified in some squamous cell carcinomas of the lung and clear cell carcinomas of the ovary.Glypican-3 is currently regarded as a tumor marker and potential target for immunotherapy.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein indistilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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