Recombinant Human Mucin-1/MUC-1/MUC1,BR

别名： Mucin-1;MUC-1;Breast carcinoma-associated antigen DF3;Cancer antigen 15-3;CA 15-3;Carcinoma-associated mucin;Episialin;H23AG;Krebs von den Lungen-6;KL-6;PEMT;Peanut-reactive urinary mucin;PUM;Polymorphic epithelial mucin;PEM;Tumor-associated epithelial membrane antigen;EMA;Tumor-associated mucin;CD227;MUC1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Mucin-1，is a membrane-bound protein that is a member of the mucin family.Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces.These proteins also play a role in intracellular signaling.This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung，breast stomach and pancreas.MUC-1 exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells.MUC-1 can act both as an adhesion and an anti-adhesion protein.This protein may provide a protective layer on epithelial cells against bacterial and enzyme attack.MUC-1 participated in modulates signaling in ERK，SRC and NF-kappa-B pathways.In activated T-cells，MUC-1 influences directly or indirectly the Ras/MAPK pathway.MUC-1 promotes tumor progression and regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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