Recombinant Human AGER/RAGE,BR

别名： Advanced Glycosylation End Product-Specific Receptor;Receptor for Advanced Glycosylation End Products;AGER;RAGE
中文名称: Recombinant Human AGER/RAGE
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,PH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Advanced Glycosylation End Product-Specific Receptor (AGER) belongs to the immunoglobulin superfamily of cell surface molecules.It lies within the major histocompatibility complex (MHC) class III region on chromosome 6.Besides AGEs，AGER is also able to bind other ligands which is thought to result in pro-inflammatory gene activation.It is known that AGER serve as a mediator of both acute and chronic vascular inflammation in certain conditions such as atherosclerosis and in particular as a complication of diabetes.Furthermore，it plays an important role in regulating the production/expression of TNF-alpha，oxidative stress，and endothelial dysfunction in type 2 diabetes.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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