Recombinant Human ALK-4/Activin RIB/Activin Receptor IB/ACVR1B,BR

别名： Activin Receptor Type-1B;Activin Receptor Type IB;ACTR-IB;Activin Receptor-Like Kinase 4;ALK-4;Serine/Threonine-Protein Kinase Receptor R2;SKR2;ACVR1B;ACVRLK4;ALK4
英文名称： Recombinant Human ALK-4/Activin RIB/Activin Receptor IB/ACVR1B
中文名称： Recombinant Human ALK-4/Activin RIB/Activin Receptor IB/ACVR1B
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Activin Receptor Type-1B (ACVR1B) is a single-pass type I membrane protein that belongs to the protein kinase superfamily.ACVR1B contains one GS domain and one protein kinase domain and is expressed in many tissues，most strongly in kidney，pancreas，brain，lung，and liver.ACVR1B acts as a transducer of activin or activin like ligands signals.Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B，ACVR2A or ACVR2B activating ACVR1B through phosphorylation of its regulatory GS domain.They go on to recruit the R-SMADs，SMAD2 and SMAD3.ACVR1B also transducers signals of nodal，GDF-1，and Vg1.Mutations in ACVR1B are associated with pituitary tumors.
来源： Human Cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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