Anti-AKT1 Polyclonal Antibody,BR

英文名称： Anti-AKT1 Polyclonal Antibody
中文名称： 蛋白激酶B抗体
规格： 50ul ; 100ul
宿主： Rabbit
亚型： IgG
交叉反应： Rat ; Mouse ; Human预测
交叉反应： Chicken;Dog;Pig;Cow;Rabbit;Sheep
应用： WB
稀释比例： WB 1:1000-5000.

靶标： AKT1
别名： AKT 1;AKT;AKT1;AKT-1;AKT1_HUMAN;C AKT;cAKT;MGC9965;MGC99656;Oncogene AKT1;PKB;PKB alpha;PKB-ALPHA;PRKBA;Protein Kinase B Alpha
背景说明： The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Swiss Prot： P31749
Gene ID： 207
亚细胞定位： Nucleus Cytoplasm Cell membrane
研究领域： 免疫学 ; 神经学 ; 新陈代谢 ; 细胞生物学 ; 发育生物学 ; 信号传导
免疫原： A synthetic peptide of human AKT1Public Immunogen Range 401-479/479aa
理论分子量： 48/56kDa

纯化方法： Affinity purification
储存液： 0.01M TBS (pH7.4) with 1% BSA， 0.02% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.
运输条件： 冷冻运输

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。