Anti-ADORA2A Polyclonal Antibody,BR

英文名称： Anti-ADORA2A Polyclonal Antibody
中文名称： 腺苷A2b受体/神经生长因子1受体抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Mouse ; Rat ; Human
应用： WB ; IF/ICC ; ELISA
稀释比例： WB 1:500-1000. IF/ICC 1:50-200.

靶标： ADORA2A
别名： Adenosine Receptor A2a,Adenosine A2A-R,A2AR,A2A adenosine receptor,A2AAR,A2aR,ADENO,Adenosine A2 receptor,Adenosine A2a receptor,Adenosine receptor subtype A2a,Adenosine Receptor A2a,ADORA 2,ADORA2,Adora2a,hA2aR,RDC 8,RDC8,AA2AR_HUMAN
背景说明： This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
Swiss Prot： P29274
Gene ID： 135
亚细胞定位： Cell membrane Multi-pass membrane protein
研究领域： 心血管 ; 免疫学
免疫原： A synthetic peptide of human ADORA2APublic Immunogen Range 300-400aa
理论分子量： 45kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

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