小鼠羧肽酶B1检测yabo官网手机版 盒,BR

中文名称： 小鼠羧肽酶B1检测yabo官网手机版 盒
英文名称： Mouse CPB1 ELISA Kit
别名： carboxypeptidase B; carboxypeptidase B1 (tissue); Carboxypeptidase B1; CPB; CPB1; DKFZp779K1333; EC 3.4.17; EC 3.4.17.2; Pancreas-specific protein; PASP; PCPB; procarboxypeptidase B
储存条件： 2-8℃，6 months
规格： 96T ; 48T
检测目标： Carboxypeptidase B1 /CPB1
样品类型： 血清/血浆/细胞培养上清
反应性： Mouse
应用： ELISA
定量/定性： 定量检测
检测范围： 12.5-800pg/mL
灵敏度： 6.25pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%

背景说明： Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.

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