小鼠骨形态发生蛋白4检测yabo官网手机版 盒,BR

中文名称： 小鼠骨形态发生蛋白4检测yabo官网手机版 盒
英文名称： Mouse BMP4 ELISA Kit
别名： BMP2B; BMP-2B; BMP2B1; BMP2BMCOPS6; BMP4; BMP-4; Bone morphogenetic protein 2B; bone morphogenetic protein 4; DVR4; MCOPS6; OFC11; ZYME
储存条件： 2-8℃，6 months
规格： 96T ; 48T
检测目标： BMP4
样品类型： 血清/血浆/细胞培养上清
反应性： Mouse
应用： ELISA
定量/定性： 定量检测
检测范围： 12.5-800pg/mL
灵敏度： 6.25pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%
反应时间： 3h15min

Swiss Prot： P21275
Gene ID： 12159
背景说明： Bone morphogenetic protein 4 (BMP4) is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. This particular family member plays an important role in the onset of endochondral bone formation in Mouses. It has been shown to be involved in muscle development, bone mineralization, and uteric bud development. In Mouse embryonic development, BMP4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog (released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures.BMP4 stimulates differentiation of overlying ectodermal tissue.BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is overexpressed (1). Increase in expression of BMP4 has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.

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