Human CD147(Mammalian，C-6His),BR

规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily，which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain.EMMPRIN is a transmembrane glycoprotein with different forms，resulting from different modes of glycosylation and N-terminal sequence variants.EMMPRIN can be expressed in breast cancer，oral squamous cell carcinoma，glioma，lymphoma，lung，bladder，and melanoma carcinomas cells.EMMPRIN promotes invasion，metastasis，growth，and survival of malignants cells，serves as a receptor for extracellular cyclophilinthe，may play a role in signal transduction.

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