Recombinant Mouse CD40/TNFRSF5/CD40L Receptor,BR

别名： Tumor Necrosis Factor Receptor Superfamily member 5;B-Cell Surface Antigen CD40;Bp50;CD40L Receptor;CDw40;CD40;TNFRSF5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

背景说明： CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily.CD40 is expressed in B cells，follicular dendritic cells，dendritic cells，activated monocytes，macrophages，endothelial cells，vascular smooth muscle cells，and several tumor cell lines.The extracellular domain of CD40 is characterized by Cysteine rich repeat regions.Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules，which in turn interact with cytoplasmic components to initiate signaling pathways.Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction.CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching，memory B cell development，and germinal center formation.
来源： Human Cells

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Mouse CD40L Receptor is produced by our Mammalian expression system and the target gene encoding Leu20-Arg193 is expressed with a Fc tag at the C-terminus.

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