Recombinant Mouse S100 Calcium Binding Protein B/S100B,BR

别名： Protein S100-B;S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-binding protein B;S100b;S100 beta;S100 calcium binding protein B
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

背景说明： S100-B，is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family.S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft.S100-B plays an important role in neurodevelopment，differentiation，and brain construction.S100-B has neuroprotective effects，but at high concentrations S100-B is neurotoxic.Extracellular concentration of S100-B increases following brain damage，which easily penetrates into cerebrospinal fluid in brain damage and then into the blood.S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS，and the astrocytes are the major cells producing S100-B protein in gray matter，as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter.The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop，enabling timely delivery of crucial medical intervention before irreversible damage occurs.In addition，S100-B，which is also present in Mouse melanocytes，is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
来源： E.coli

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Mouse S100 Calcium Binding Protein B is produced by our E.coli expression system and the target gene encoding Met1-Glu92 is expressed with a 6His tag at the C-terminus.

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