Recombinant Mouse IFN γ R1/CD119(Fc fusion),BR

别名： CD119;Interferon gamma receptor 1;IFNGR1;IFN-gamma receptor 1;IFN-gamma-R1;CD119 antigen;IFN gamma receptor 1;IFNGR;immune interferon receptor 1;interferon gamma receptor 1;interferon-gamma receptor alpha chain
英文名称： Recombinant Mouse IFN gamma R1/CD119(Fc fusion)
中文名称： 重组小鼠IFN gamma R1/CD119(Fc fusion)
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： The tetrameric receptor complex for IFNγ consists of two subunits，IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ)，through which the dimeric IFN-γ exerts its biological functions，including antiviral，antiproliferation and immune-modulatory activity in mammals.Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family.FNGR1，widely expressed in most host cells，is essential for IFNγ binding，receptor trafficking，and signal transduction.IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site，a signal transducer and activator of transcription 1 (STAT1) binding site.The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).
来源： Human cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Mouse Interferon gamma Receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala26-Asp253 is expressed with a Fc tag at the C-terminus.

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