Recombinant Mouse Semaphorin 4A/SEMA4A,BR

别名： Semaphorin-4A;Semaphorin-B;Sema B;Sema4a;Semab;SemB
英文名称： Recombinant Mouse Semaphorin 4A/SEMA4A
中文名称： 重组小鼠Semaphorin 4A/SEMA4A
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain，a PSI domain and a Sema domain.SEMA4A is expressed from day 10 in the embryo，and low levels are found between days 10-12.SEMA4A is a cell surface receptor for PLXNB1，PLXNB2，PLXNB3 and PLXND1 that plays an important role in cell-cell signaling.It plays a role in priming antigen-specific T-cells，promotes differentiation of Th1 T-helper cells，and thereby contributes to adaptive immunity.SEMA4A promotes phosphorylation of TIMD2，inhibits angiogenesis，and promotes axon growth cone collapse，Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
来源： Human cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Mouse Semaphorin 4A is produced by our Mammalian expression system and the target gene encoding Thr33-His682 is expressed with a 6His tag at the C-terminus.

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