Recombinant Human FCGRT & B2M Heterodimer,BR

别名： IgG receptor FcRn;Neonatal Fc receptor;FCRN
英文名称： Recombinant Human FCGRT & B2M Heterodimer
中文名称： 重组人FCGRT & B2M Heterodimer
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM HEPES,150mM Nacl,pH7.4.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51（alpha chain) and Beta-2-microglobulin（Beta chain).The complexes is similar in structure to MHC class I-like heterodimer.Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system.FcRn binds to the Fc region of monomeric immunoglobulins gamma，mediates the uptake of IgG from milk，Possible role in transfer of immunoglobulin G from mother to fetus.A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin，a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
来源： Human cells

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human IgG Fc fragment receptor transporter is produced by our Mammalian expression system and the target gene encoding Ala24-Leu290&Ile21-Met119 is expressed with a 6His tag at the C-terminus.

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