Recombinant Human AG-2/HPC8/AGR2,BR

别名： Anterior Gradient Protein 2 Homolog;AG-2;hAG-2;HPC8;Secreted Cement Gland Protein XAG-2 Homolog;AGR2;AG2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris,200mM NaCl,10％Glycerol，pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： The product is shipped on dry ice/ice packs.

背景说明： Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes.AGR2 is widely expressed in secretory cells，such as small intestine goblet，prostate epithelium，enteroendocrine cells，and multiple carcinoma cell types.AGR2 forms transient disulfide linkages with molecules destined for secretion，possibly aiding protein folding.Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor.Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175).Cys81 is presumed to participate in intermolecular bond formation.Over aa 21 - 175，human AGR2 shares 94% aa identity with mouse AGR2.
来源： Human cells

内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human Anterior Gradient Protein 2 Homolog is produced by our Mammalian expression system and the target gene encoding Arg21-Leu175 is expressed with a 6His tag at the C-terminus.

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