Recombinant Human Legumain/Asparaginyl Endopeptidase,BR

别名： Legumain;Asparaginyl Endopeptidase;Protease Cysteine 1;LGMN;PRSC1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： The product is shipped on dry ice/ice packs.

背景说明： Legumain is a lysosomal cysteine protease which is a member of the peptidase C13 family.Though it is found in many tissues，it is highly expressed in the kidney，heart，and placenta.Legumain has a strict specificity for hydrolysis of asparaginyl bonds and can also cleave aspartyl bonds slowly，especially under acidic conditions.Over-expression Legumain in tumors is significant for invasion and metastasis.In addition，Legumain may be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system and negative regulation of neuron apoptosis.
来源： Human cells

内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human Legumain/Asparaginyl Endopeptidase is produced by our Mammalian expression system and the target gene encoding Ile18-Tyr433 is expressed with a 6His tag at the C-terminus.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。