Recombinant Human CNTF/Ciliary neurotrophic factor,BR

别名： Ciliary Neurotrophic Factor;CNTF
英文名称： Recombinant Human CNTF/Ciliary neurotrophic factor
中文名称： 重组人CNTF/Ciliary neurotrophic factor
规格： 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
纯度： ≥95% as determined by reducing SDS-PAGE.
储存条件： Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： 冷藏运输

背景说明： Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes.CNTF has also been shown to prevent the degeneration of motor axons after axotomy.CNTF is highly conserved across species and exhibits cross-species activities.Human and rat CNTF share approximately 83% homology in their protein sequence.CNTF is structurally related to IL6，IL11，LIF and OSM.All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes.CNTF，like FGF acidic，FGF basic，and PD-ECGF (platelet-derived endothelial cell growth factor)，does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways.The mechanism underlying the release of CNTF is unknown.
来源： E.coli

溶剂： Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素： Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.

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